Salmon Sperm Injections Explained: Science, Benefits, and What Sets This Treatment Apart

In the ever-evolving world of advanced aesthetics, innovative aesthetic treatments are constantly emerging, but few are making waves quite like the salmon sperm injections. While the name might raise eyebrows, the science behind this cutting-edge treatment is both fascinating and results-driven. Powered by polynucleotides derived from salmon DNA, this treatment offers a powerful approach to skin regeneration, rejuvenation and repair.

At EF Medispa, we are committed to staying at the forefront of aesthetic innovation, offering treatments that are backed by clinical research and tailored to your skin’s unique needs.

In this blog, we will break down exactly what salmon sperm injections are, how they work, the key benefits it offers and why it is becoming a go-to option for those seeking radiant, youthful skin.

What are salmon sperm injections?

Despite its unusual name, salmon sperm injections (or salmon sperm facials) also known as polynucleotide treatment, is a scientifically advanced, injectable skin therapy. It is designed to stimulate deep skin regeneration across targeted areas or the full face, depending on individual needs. The treatment uses biocompatible polynucleotides, which are DNA fragments derived from salmon sperm. These molecules closely resemble human DNA, making them highly compatible with our bodies and ideal for encouraging natural healing processes.

Polynucleotides work by improving cell turnover, enhancing hydration and boosting collagen production, all of which contribute to a healthier, more youthful-looking skin. Far from being a gimmick, this treatment is rooted in clinical science and is rapidly gaining popularity for its ability to address a range of skin concerns with minimal downtime.

The science behind polynucleotides and the key benefits

Polynucleotides are DNA fragments derived from salmon sperm that offer powerful regenerative benefits for the skin. Once injected, they act as bio-stimulators, helping to repair and revitalise skin from within.

Here is how they work:

• Stimulate fibroblast activity: Polynucleotides activate fibroblasts, the cells responsible for producing collagen and elastin. This helps to restore skin firmness and elasticity.
• Boost collagen and elastin production: With increased collagen and elastin, skin becomes smoother, plumper and more resilient over time.
• Improve skin hydration: These molecules attract and retain moisture, leading to better hydration and a dewy, refreshed appearance.
• Enhance microcirculation: Improved blood flow means more oxygen and nutrients are delivered to skin cells, promoting a healthy, radiant glow.
• Neutralise free radicals: Polynucleotides have antioxidant properties that protect the skin from environmental damage and premature ageing.
• Support deep tissue regeneration: Unlike surface level treatments, polynucleotides work on a cellular level to encourage long-term skin repair and renewal.

This multi-action approach makes polynucleotide therapy a standout in the world of advanced skin rejuvenation.

How do salmon sperm injections compare to other skin boosters?

While traditional skin boosters like hyaluronic acid (HA) fillers and mesotherapy have long been used to hydrate and plump the skin, polynucleotide-based treatments offer a more regenerative approach. Rather than simply enhancing the skin’s appearance temporarily, salmon sperm injections work on a deeper level to repair and revitalise the skin over time.

Comparison with other skin boosters:

Salmon sperm injections:

• Stimulate collagen and elastin production for long-term rejuvenation
• Repairs damaged tissue at a cellular level
• Deeply hydrates and improves overall skin elasticity
• Reduces inflammation and supports healing
• Results improved with continued treatment and last longer
• Minimal downtime, with a gradual but noticeable transformation
• Ideal for ageing, dull, tired or compromised skin 

Hyaluronic acid skin boosters (e.g. Profhilo)

• Attract and retain moisture to plump and hydrate the skin
• Offer a quick skin refresh with immediate results
• Improve fine lines and boost glow, but effects are temporary
• Minimal stimulation of collagen or long-term regeneration
• Best for dehydrated or mildly ageing skin

Mesotherapy:

• Delivers a cocktail of vitamins, enzymes and amino acids to the skin
• Targets dullness, uneven tone and superficial signs of ageing
• Results vary based on the ingredients used
• Minimal collagen stimulation
• Best for those wanting a gentle boost or maintenance treatment 

Why choose polynucleotides?

While HA boosters offer instant hydration and a temporary plumping effect, polynucleotides work over time to improve skin health from the inside out. They are ideal for patients seeking more sustainable, long-term rejuvenation, especially for concerns like:

• Skin laxity
• Acne scarring
• Early signs of ageing

What skin concerns can salmon sperm injections address?

Thanks to its regenerative and anti-inflammatory properties, salmon sperm injections offer a versatile treatment that targets both aesthetic and functional skin concerns. Unlike many traditional boosters, polynucleotides work on a cellular level, making them suitable for a wide range of skin conditions.

This treatment can help with:

• Fine lines and wrinkles
• Skin laxity
• Dull, tired looking skin
• Acne scarring
• Inflammation and redness
• Dehydrated skin
• Sun damage and pigmentation
• Under-eye hollowing and crepiness

This treatment is especially beneficial for clients looking to rejuvenate and heal their skin from within, rather than mask concerns temporarily.

Who is a good candidate for this treatment?

The salmon sperm facial is suitable for a wide range of individuals looking to improve the health, texture and appearance of their skin.

You may be a good candidate if you:

• Are experiencing early to moderate signs of ageing, such as fine lines, wrinkles or mild sagging
• Have dull, tired or dehydrated skin that lacks glow and elasticity
• Struggle with acne scars or post-inflammatory marks
• Have sensitive or redness-prone skin and are looking for a calming, healing treatment
• Want to improve the appearance of sun damage or uneven skin tone
• Are looking for a preventative anti-ageing solution to maintain skin health over time
• Prefer a minimally invasive treatment with natural looking results

At EF Medispa, a consultation with one of our experienced practitioners will help determine if this treatment is right for your skin goals and medical history.

Treatment experience: What to expect before, during and after

At EF Medispa, we prioritise comfort, safety and exceptional results throughout every stage of the procedure. Here is what you can expect throughout your salmon sperm facial journey:

Before the treatment

• A thorough consultation to assess your skin, medical history and suitability for the treatment
• Customised treatment planning based on your skin goals

During the treatment

• The skin is cleansed, and a topical numbing cream is applied to ensure comfort
• Polynucleotides are carefully injected using fine needles or a cannula, depending on the area treated
• The treatment typically takes 30-45 minutes

After the treatment

• Mild redness, swelling or pinpoint marks may appear. These usually subside within 24-48 hours
• Minimal downtime, most clients return to daily activities the same or next day
• Post-treatment care includes gentle skincare, hydration and avoiding strenuous activity or heat for 24-48 hours 

How long do results last and how many sessions are needed?

Polynucleotide treatments work gradually, as they stimulate natural regeneration over time. Visible improvement typically becomes noticeable within a few weeks of the first session.

For best results:

• Initial course: 3 sessions spaced 2-4 weeks apart
• Maintenance: 1 session every 4-6 months, depending on your skin’s needs

Results can include:

• Firmer, smoother and more hydrated skin
• Reduction in fine lines, texture irregularities and dullness
• A long-lasting improvement in overall skin quality

Unlike traditional fillers, the effects of polynucleotides are cumulative and improve over time as the skin rebuilds and regenerates.

Salmon sperm injections with EF Medispa

As a leader in advanced, medically led skincare, EF Medispa is proud to offer salmon sperm injections (polynucleotide therapy) as part of our cutting-edge regenerative treatments. Our expert team combines clinical knowledge with personalised care to deliver safe, natural-looking results tailored to your skin’s unique needs.

Whether you are just starting your aesthetic journey or seeking a powerful skin rejuvenation boost, the salmon sperm facial offers a scientifically proven way to restore radiance, firmness and vitality.

Book your consultation at one of our London clinics today and let our expert team create a personalised treatment plan tailored to your skin’s needs.