NeoGen Plasma, Cosmelan and Dermamelan in London

Pigmentation Treatment in London

Sun spots, melasma and dark marks. Cleared, not covered.

Pigmentation has more than one cause, so we have more than one answer. NeoGen Plasma regenerates sun-damaged skin, evening tone while it smooths and firms, and the Cosmelan and Dermamelan methods by mesoestetic treat stubborn pigment and melasma at the source. We match the right one to your skin at a complimentary consultation.

Or see the calendar and book online

★★★★★ average 4.5 on Google See the results
Before and after images in this film are from the official NeoGen website. Treatments carried out by NeoGen. Individual results may vary.
  • Nineteen years of expertise
  • Three London clinics
  • 250,000+ treatments performed
  • Multi-award winning
Safety in Beauty Diamond Award 2016 Professional Beauty Awards 2018 My Face My Body Awards Winner 2015 London Lifestyle Awards 2017 Winner

Our Kensington clinic is regulated by the Care Quality Commission (ID 1‑129888578). View our registration

NeoGen Plasma: see it for yourself.

Sun damage, uneven tone, texture and the delicate eye area, treated together as the skin regenerates. Results keep building for up to 12 months after treatment.

  • NeoGen Plasma before and after, eye area
  • NeoGen Plasma before and after, full face
  • NeoGen Plasma before and after, side profile
  • NeoGen Plasma before and after, side profile
  • NeoGen Plasma before and after
  • NeoGen Plasma before and after
  • NeoGen Plasma before and after

Before and after images are shown for illustration. Individual results may vary.

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What kind of pigmentation do you have?

Pigmentation is not one condition, it is several. Identifying yours correctly is the difference between fading it and clearing it. Choose the one that sounds most like you.

Choose what you see

Sun damage with texture and fine lines

Years of UV exposure rarely leave colour alone. Uneven tone tends to arrive with rougher texture, fine lines and a loss of firmness.

We recommendNeoGen Plasma

FDA-cleared nitrogen plasma regenerates the structure of the skin, so tone, texture and tightness improve together rather than one at a time. How NeoGen works

NeoGen Plasma is available at our Chelsea and St John’s Wood clinics.

Dark circles and crepey under-eye skin

Dark, tired-looking lids and thin, crepey skin around the eyes, where most treatments cannot go.

We recommendNeoGen Plasma

Nitrogen plasma can be used right up to the lash line, brightening and tightening dark, tired-looking lids. How NeoGen works

NeoGen Plasma is available at our Chelsea and St John’s Wood clinics.

Sun spots and age spots

Small dark patches on the face, hands and décolletage, caused by years of UV exposure triggering excess melanin.

We recommendCosmelan

The professional depigmenting method by mesoestetic that visibly reduces discolouration and helps keep it from returning. When spots come with texture, lines or laxity, NeoGen Plasma treats them together. How the method works

Melasma and hormonal pigmentation

Larger, irregular patches driven by hormones, pregnancy, contraception or sun. Often called the “pregnancy mask”.

We recommendDermamelan

Regulates the enzyme that produces melanin, treating stubborn pigment at its source rather than bleaching the surface. How the method works

Light and heat can make melasma worse, which is why we assess it in person before recommending anything.

Acne marks and dark marks after breakouts

Flat discolouration left behind after breakouts, injury or inflammation heals. Common in acne-prone skin.

We recommendCosmelan or Dermamelan

Lifts the discolouration left behind by breakouts while renewing skin texture. Where there is scarring too, RF Microneedling or NeoGen Plasma work on the texture.

Intimate area darkening

Darker skin in the intimate area, groin and inner thighs, often from hormones, friction or hair removal.

We recommendDermamelan Intimate

A depigmentation protocol by mesoestetic developed specifically for the intimate area, carried out discreetly and with care. How the method works

Most women arrive with more than one type, and sometimes a combination gives the best result. Your complimentary consultation confirms the right match for your skin.

Find my match at a consultation

NeoGen Plasma: regenerate, not just resurface

When sun damage brings uneven tone together with texture, fine lines or laxity, NeoGen goes deeper. Nitrogen plasma warms the whole structure of the skin without creating an open wound, so tone, texture and firmness improve together rather than one at a time.

Because the surface layer is left in place, it acts as a natural dressing while new skin forms underneath.

  • Pigmentation, texture and firmness in one planSoftens sun-induced pigmentation while smoothing texture and tightening the skin.
  • Right up to the lash lineCan be used on the delicate eye area, brightening and tightening dark, tired-looking lids.
  • Results that keep buildingTightening can be seen after one session, and results keep improving for up to 12 months as new collagen forms.
  • FDA clearedFor seven skin indications, as stated by the manufacturer. Individual results vary.
A gentle courseAlmost no downtime

Usually 3 to 5 lighter sessions around four weeks apart, with mild redness for a day or two.

One intensive treatmentThe biggest change from one visit

A single high energy session. The treated skin darkens and sheds over 5 to 7 days as new skin comes through.

Explore NeoGen Plasma

Strictly Come Dancing head judge Shirley Ballas talks about her own NeoGen Plasma treatment, which she had with NeoGen directly rather than at EF MEDISPA. At EF MEDISPA we treat with NeoGen EVO, the latest version of the same platform, at our Chelsea and St John’s Wood clinics.

Cosmelan and Dermamelan by mesoestetic

Described by mesoestetic as the world’s leading professional depigmentation method. Rather than bleaching the surface, it regulates melanin production at its source. In mesoestetic’s reported data the method reduces pigmentation in around 95% of cases, with around 80% improvement visible after the first month. Manufacturer reported figures. Individual results vary.

  1. 01

    The in-clinic mask

    Your practitioner applies the professional depigmenting mask, which you wear for 8 to 12 hours depending on your skin type.

  2. 02

    The renewal phase

    Over 5 to 7 days your skin gently peels, lifting away built-up pigment to reveal fresher, more even-toned skin beneath.

  3. 03

    Protect and maintain

    A simple home maintenance cream and daily SPF50+ keep melanin regulated, so the pigment stays away.

For mild to moderate pigmentationCosmelan

For sun spots, mild to moderate pigmentation and first-time depigmentation treatments. The usual starting point.

For stubborn pigmentationDermamelan

The more intensive option, for stubborn, moderate to severe pigmentation and persistent melasma.

For the intimate areaDermamelan Intimate

Developed specifically for the intimate area, groin and inner thighs, where hormones, friction and hair removal often leave the skin darker.

In clinic
Up to 1 hourFor the application, then the mask stays on at home.
Sessions
OnePlus a simple home care routine.
Back to work
Around 3 daysPeeling settles within 7 to 10 days.
Results
From 2 weeksAt their best by 1 to 2 months.
Before DermamelanBefore After DermamelanAfter
Dermamelan. Individual results may vary.
Before CosmelanBefore After CosmelanAfter
Cosmelan. Individual results may vary.

Working to the manufacturer’s own protocols

Our sister brand EF SKIN is an official UK distributor of mesoestetic, the maker of Cosmelan and Dermamelan, so our practitioners are trained and supported directly on the methods they deliver.

NeoGen Plasma, Cosmelan or Dermamelan?

How the three compare on what they treat, how long they take and how much downtime to plan for. Your practitioner confirms the right one for your skin.

NeoGen PlasmaPlasma regenerationCosmelanDepigmentation methodDermamelanDepigmentation method
Best forSun damage that comes with texture, fine lines or laxity, and dark, tired-looking eyesMild to moderate sun spots and first-time depigmentationStubborn melasma and deep, persistent pigmentation
How it worksNitrogen plasma warms the whole structure of the skin without an open wound, so tone, texture and firmness improve togetherAn in-clinic depigmenting mask, then a home routine that keeps melanin regulatedThe more intensive depigmenting mask, then a home phase your practitioner tailors to you
Your courseA single high energy session, or 3 to 5 lighter sessions around four weeks apartOne session, plus simple home careOne session, plus a home phase
In clinic10 to 60 minutesUp to 1 hourUp to 1 hour
DowntimeFrom a day or two of redness to 5 to 7 days, set to suit your diaryBack to work in around 3 days. Peeling settles within 7 to 10 daysBack to work in around 3 days. Peeling is more pronounced and settles within 7 to 10 days
ResultsTightening after one session, building for up to 12 monthsFrom 2 weeks, at their best by 1 to 2 monthsFrom 2 weeks, at their best by 1 to 2 months
AreasFace, eyes, neck, chest and handsFace. Other areas assessed at consultationFace, plus the intimate area, groin and inner thighs with Dermamelan Intimate
WhereChelsea and St John’s WoodAll three clinicsAll three clinics

We also offer chemical peels for brightening and maintenance, RF Microneedling where acne marks come with scarring, and laser resurfacing for sun damage alongside texture change. Courses, timings and downtime are typical ranges and vary from person to person.

Is pigmentation treatment right for me?

Your consultation includes a full medical history and an assessment of your skin, and we only go ahead if treatment is safe and right for you. If a different approach would serve you better, you will be told honestly.

Not sure which treatment suits your concern? Try our Treatment Guide.

It’s often a good fit if

  • You have sun spots, melasma, acne marks or uneven tone you’d like cleared, not covered
  • Your pigmentation comes with texture, fine lines or crepey eyes, which NeoGen Plasma treats together
  • You’d like a method designed for all skin phototypes: Cosmelan and Dermamelan are made to be used across them
  • You’re happy to follow a simple home routine and wear SPF50+ every day

Talk to us first if

  • Your pigmentation is hormonal. It can return with new triggers, so we plan maintenance with you
  • You’re considering light or laser treatment for melasma, where light and heat can make pigmentation worse
  • You have a medical condition or take any medication. Tell us at your consultation, where we take your full medical history

Every plan is tailored to you, and results vary from person to person.

From consultation to clearer skin

Pigmentation is complex. Results come from expert diagnosis, not just technology. Here is what to expect.

  1. Your complimentary consultation

    We assess your skin, identify your pigmentation type, whether melasma, sun damage or post-inflammatory, and take your full medical history. There’s no obligation to go ahead.

  2. Your bespoke plan

    Your treatment, or combination of treatments, is matched to your pigmentation, skin tone and lifestyle, including how much downtime suits you.

  3. Your treatment

    NeoGen Plasma takes 10 to 60 minutes in clinic. For Cosmelan or Dermamelan, your practitioner applies the depigmenting mask, which you wear for 8 to 12 hours depending on your skin type.

  4. Renewal

    After Cosmelan or Dermamelan your skin gently peels over 5 to 7 days. After NeoGen, expect anything from a day or two of redness to 5 to 7 days as the treated skin sheds, depending on the energy chosen.

  5. Protect and maintain

    A simple home care routine and daily SPF50+ lock in your results and help keep pigment from returning. We guide you through both and plan maintenance with you.

Book your complimentary pigmentation consultation

Tell us a little about you and a member of our team will be in touch within 24 hours to answer your questions and find a time that suits you.

Request your consultation

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Your consultation request has been received. A member of our team will be in touch within 24 hours.

  • Complimentary, with no obligation to go ahead
  • A reply within 24 hours from a member of our team
  • Your pigmentation type identified before anything is recommended

Prefer to choose your own time?

See available times at your nearest clinic and book online straight away.

See the calendar and book online

Prefer to call? Our three clinics:

Complimentary consultations exclude medical and doctor appointments, which may incur a fee.

How much does pigmentation treatment cost?

Every plan is personal to your pigmentation type, the method chosen and any treatments we combine, so we talk you through your options and your investment at your complimentary consultation rather than online. There is no obligation to go ahead.

What do our patients say?

Reviews left on Google by patients at our Kensington, Chelsea and St John’s Wood clinics.

4.5

Average rating on Google across our three London clinics.

★★★★★

“Yana is the best! Super thorough and gives the best results. Does not rush treatments, takes time and care to give the best possible treatment and is friendly and welcoming. Would keep coming just for Yana!”

★★★★★

“Faten is exceptionally professional and meticulous. She personalizes each treatment, delivering impressive results. Highly recommended!”

★★★★★

“Wonderful team. A special thanks to the wonderful Lara who was very attentive toward me and went out of her way to accommodate me.”

Your questions, answered

Can’t see your question? Our patient team is happy to help on 0207 361 1000.

What is the best treatment for pigmentation?

It depends on your pigmentation type and how deep it sits. NeoGen Plasma is ideal when sun damage comes with texture, fine lines or laxity, including around the eyes. Cosmelan suits mild to moderate pigmentation and sun spots, Dermamelan is the more intensive option for stubborn cases and melasma, and Dermamelan Intimate is the route for darkening in the intimate area. Your complimentary consultation confirms the right match, and sometimes a combination gives the best result.

Does NeoGen Plasma treat pigmentation?

Yes. NeoGen Plasma softens sun-induced pigmentation while it smooths texture and tightens the skin. Nitrogen plasma warms the whole structure of the skin without creating an open wound, so tone, texture and firmness improve together. Results keep building for up to 12 months as new collagen forms.

Can you treat dark circles under the eyes?

Yes. NeoGen Plasma can be used right up to the lash line, brightening and tightening dark, tired-looking lids and crepey under-eye skin.

Does it work for melasma?

Melasma is one of the concerns the Dermamelan method was designed for. It works by regulating the enzyme responsible for melanin production, treating melasma at its source rather than just the surface, and the home maintenance phase helps keep it from returning. In mesoestetic’s reported data the method reduces pigmentation in around 95% of cases, with visible improvement in the first month. Individual results vary, which is why we assess your melasma in person first.

What is the difference between Cosmelan and Dermamelan?

Both are depigmentation methods by mesoestetic that regulate melanin production at its source. Cosmelan is for mild to moderate pigmentation, sun spots and first-time depigmentation treatments. Dermamelan is the more intensive option, for stubborn, moderate to severe pigmentation and persistent melasma, and it is also available as Dermamelan Intimate for the intimate area.

How does the Cosmelan and Dermamelan treatment work?

Your practitioner applies a professional depigmenting mask in clinic, which you wear for 8 to 12 hours depending on your skin type. Over the next 5 to 7 days your skin gently peels, lifting away built-up pigment. A simple home maintenance cream and daily SPF50+ then keep melanin regulated so the pigment stays away.

What is the downtime?

Cosmelan and Dermamelan involve 5 to 7 days of gentle peeling, and most clients are back at work in around 3 days with the right home care. NeoGen Plasma is tailored to you: a gentle course brings a day or two of mild redness, while a single high energy treatment means 5 to 7 days as the treated skin darkens and sheds.

When will I see results?

With Cosmelan and Dermamelan, results show from around 2 weeks and are at their best by 1 to 2 months. With NeoGen Plasma, tightening can be seen after one session and results keep building for up to 12 months. Individual results vary.

Is it suitable for darker skin tones?

Cosmelan and Dermamelan are designed by mesoestetic to be used across all skin phototypes, which is one reason they are so widely used for melasma and post-inflammatory pigmentation. Your practitioner assesses your skin at consultation and confirms the safest, most effective option for your tone, including whether a light or energy-based treatment is appropriate for you.

Can you treat darkening in the intimate area?

Yes. Dermamelan Intimate is a depigmentation protocol by mesoestetic developed specifically for the intimate area, groin and inner thighs, where hormones, friction and hair removal often leave the skin darker. It follows the same principle as Dermamelan for the face: an in-clinic treatment followed by a simple home routine, carried out discreetly and with care. We talk it through with you privately at your complimentary consultation.

Can acne marks be treated?

Yes. Cosmelan or Dermamelan lift the discolouration left behind by breakouts while renewing skin texture. Where acne has also left scarring, RF Microneedling or NeoGen Plasma work on the texture, and the two approaches can be combined.

Will my pigmentation come back?

The depigmentation method does not just remove existing pigment, it regulates melanin production to help prevent it reappearing. Your home maintenance phase and daily SPF50+ are the keys to keeping results long term, and we guide you through both. Hormonal pigmentation can return with new triggers, so we plan maintenance with you.

Is IPL or laser good for melasma?

Not usually. Light and heat can make melasma worse, which is why we assess your pigmentation in person and often recommend Dermamelan, which regulates pigment at its source.

How much does pigmentation treatment cost?

Every plan is personal to your pigmentation type, the method chosen and any treatments we combine, so we talk you through your options and your investment at your complimentary consultation rather than online. There is no obligation to go ahead.

Which EF MEDISPA clinics offer pigmentation treatment?

Cosmelan and Dermamelan are available at all three of our clinics: Kensington on Kensington Church Street, Chelsea on the Kings Road and St John’s Wood on St John’s Wood High Street. NeoGen Plasma is available at Chelsea and St John’s Wood.

Where can I have pigmentation treatment in London?

Cosmelan and Dermamelan are available at all three of our clinics, and NeoGen Plasma at Chelsea and St John’s Wood. Call or WhatsApp your nearest one.

Kensington

Address
29 Kensington Church Street, London W8 4LL
Treatments
Cosmelan, Dermamelan
Stations
High Street Kensington, Olympia
Open
Tuesday and Wednesday 9am to 6pm, Thursday 11am to 8pm, Friday 10am to 7pm, Saturday 10am to 6pm. Closed Sunday and Monday.

Chelsea

Address
193 Kings Road, London SW3 5ED
Treatments
NeoGen Plasma, Cosmelan, Dermamelan
Stations
Sloane Square, South Kensington
Open
Monday to Friday 9am to 8pm, Saturday 9am to 7pm. Closed Sunday.

St John’s Wood

Address
69 St John’s Wood High Street, London NW8 7NL
Treatments
NeoGen Plasma, Cosmelan, Dermamelan
Station
St John’s Wood
Open
Tuesday and Wednesday 9am to 6pm, Thursday and Friday 10am to 7pm, Saturday 10am to 6pm. Closed Sunday and Monday.

Trusted for Results Since 2007